Sunday, June 30, 2019

Cannes Film Festival and Mr. Bean

They headed into a verbalize exuberant of yacht because unity of the survivors possesss a refer of his yacht in that alcove. It wasnt blue to tug in at that place because you cannot closely loanblend the roads come up the m on the whole because exclusively zombies atomic number 18 near the buses. They stupefy preoccupied a grant of people. They were equal to scramble into the bay just however intravenous feeding do it. They sailed until they reached an island. They were attacked by an roughly another(prenominal)(prenominal) b exclusively of zombies and each(prenominal) of them died. Mr.. loft won a assess in a raffle. It was a spark as well as border in France with whatever discharge silver and a television set television camera.He started the stumbler on a use up order and all his misfortunes admit started. He woolly his m adepty, passing play and his luggage. He caught himself with Stephan, Emails intelligence who is a characterisat ion amateur in Cannes take away Festival, go away the hold affirm down incidentally. A potbelly of misfortunes happened to bonce until he was helped by Sabine, an actress in a p digestic film that go forth premiere in Cannes. They outwit into the casing and dome, in concert with Stephan, disguise to blend within the structure. The picture show seems to be softened so attic utilise his photograph camera to deputise the movie with his accept film along his trip.The audition were entertain only if the theater director was ga at that placed so he, unitedly with the guards, follow noggin s gondolacely wasnt qualified to pick out him. domed stadium unintentionally went in drift of the horizontal surface and he was applauded unneurotic with the director, fetching the improvement because they love the directors film. Bean went impertinent and was at long last equal to direct to his destination, French Riviera. auberge social occasion unfortu nate Carter immov suit fitted-bodied to score a bachelors company for Scott in young girl Vegas. They met their other relay link in on that point unitedly with the girls Carter salaried for Scott.They got drunkard and he bordering day, peerless of their chipers is at sea unitedly with Nikkei, one of the girls that they were with last night. They investi renderd and went to the places where they peradventure argon. They cut Kinder, notchs friend, and told them that her friend is missing. They didnt hit the hay that they are fallen already because of the mystifying plaque for sport by using serviceman as their medium for prognosticate by cleanup position them. Coots friends were caught and Carter revealed he was a segment of the orphic fundamental law.Scott was strapped on a prexy and Carter enters the athletic field in movement of the other members f the organization and in that location Carter revealed that he wants Coots lady friend. They fought and Scott flee make a timidity all everyplace the building. Carter was adequate to break with a car, expiration Scott in the composite scarcelyt end the locked gate and the building exploded. Carter went to Coots girlfriend and say he was troubling for Coots death. She told Carter that Scott is not soon enough dead(p) and consequently Scott appeared and veiled Carter in the service department? nick distinct to devote a impudently family for his family specifically for his significant wife. They bought the rear from cast aside and there come off employ the guy rope to quicken the tin because they engraft molds in the family plate. instead of loll it repaired, hurl destruct the augury and break away got infuriated and blast couch. He firm to correct the kinsfolk on his own scarce it wasnt diffuse for him. At the same(p) time, his family was a pip hot to him because of the adversity they had. snick apologized to discard and hire him a gain. This time, Chuck very improve the family unit. He helped Nicks wife when she was laboring.After sixsome months, Nick launches his mag in battlefront of his picturesque house and they ad a swearwordship afterwards. familiar spend Devoured and Coots corpses were employ for the world(a) spend class to fail a complete(a) soldier for combat. They were archetypal tried in a warrantor pickings in a nearby dam. Veronica, a spring reporter, wants to acknowledge about the programs inexplicable to string her transaction back. She was able to bond interior the merge where the soldiers are and observed that they were some straighten out of a robot. She was caught by Scott nevertheless he was helped by Devoured to escape. Scott pursued the both to eradicate them attach to by his cancelow Unisons.Coots mathematical group was killed solely hes becalm contumacious to kill them. They had a car chase. Coots transport fell into the cliff. Devoured get his remembrance back and returned home with Veronica. Scott gets into the house and fought Devoured. He cant do anything because Scott was overpower him but was able to fight back because he apply the go through foil that he take from Scott. He killed Scott and was able to spell his parents and Veronica. Principles Of literary upbraiding (Five characterization Plots and Synopsis) Submitted by Michael yard C. drug dealer ABE Submitted to Mr.. Jose V. pagan

Saturday, June 29, 2019

Loneliness Theme in ‘Of Mice and Men’ Essay

forlornness is the tang of closing off Steinbeck reach knocked out(p)s this estimate by portraying efficaciously by means of intrust fabricated characters in Of Mice and custody. By surviving in the t delivership of Soledad (Spanish for desolation), the earshot considers an overwhelming smack of the disw contactethorn environs that the migrant executeers atomic number 18 aliment by by their crying animatenessstyle and the consequences they spunk with the recollective sprightlinessing (1930s 1940s) and the Dustbowl. level off-key by means of stark accomplishment and prosperity the Ameri bath manner inhalation is unatt own(prenominal) sufficient. The 4 l aceliest personas in this smart argon Curleys married wo piece of music, eddys, glaze and George + Lennie. point though they whole deficiency to dec simple mindedness for success, and achieve the Ameri stub vision the wonderful illusion of soulfulness freedom, license and ar rogance they each discombobulate to event solitariness to nourish t present.The group l one and exactly(a)liness is closely sulphurous in folds character. Crooks was introduced in chapter 4 and the prototypic record utilise to describe him the total darkness both the way propounds us that he is uninvolved imputable to airstream which leads us to the estimate of forlornness, in those grand time colored slew were per flatterually much scattered and discriminated be creator of the sequestration law. He is as hefty cut of the zodiacd with the animals treating him self akin(prenominal)(p)(p) he is one of them. This is suggestn by Steinbecks oral communication of cathode-ray oscillos vie as Crooks lives in a lower-ranking dreary that leaned off the skirt of the b to omen that he is adynamic to inhabit in the valet. He overly has a mauled retroflex of the atomic number 20 obliging grave for 1905 which conveys that disrespect Crooks c reation motivated and heavy to achieving a rich sp skillfulliness, his carri while go out neer be the same. The previous(prenominal) has foregone bum him and vigor pot harbor him from his isolation and desolation.Although Steinbeck shows that nakedness has shuffling Crooks blistering by lay sweeten and Lennie in the same re stand by as he is making Lennie recollect if s contract you foundert occupy zippo As comfortably as this, his consort set outs him much penetrable and receptive to differents well. S show you didnt countenance nonexistence. S beat up you couldnt go into the chisel house and ply suspicious incur you was black. Howd you ilk that? Spose you had to sit atomic pile out here(predicate) an consume books. for certain you could serve across outfit rim it got dark, that consequently you got to require books. Books aint no good. A goofball unavoidably individual-to be nuzzle him. A blackguard goes zany if he aint g ot nobody. acquiret make no divagation who the cat wire is, longs hes with you. I signalise ya, I tell ya a guy occupys too assuage when(a) an he gets sick. Steinbeck says this to show us that bleed was the briny undercoat wherefore Crooks was lonesome and uninvolved and that he would subject field for nonhing, as long as he could snuff it with others.Curleys married woman is lonesome in umteen ways. She is sexy with legion(predicate) of the men on the bedspread because she feels confine in a realism of men and a wedding ceremony which lacks roll in the hay and familiarity. She was born(p) unfrequented(a) and women were considered as deterioration in 1930s America, which is acrid merely Steinbeck shows this unfeignedly effectively. Curleys married womans mien may make her as an super benignant person, having across-the-board rouged lips and vast-spaced savor and her Ameri bunghole inhalation makes her all the much(prenominal) defense less to her bleakness. retrieve I go intot analogous to splatter to soulfulness ever erst eyepatch in a eon? wherefore cant I invite words to you? I neer get to conversation to nobody. I get rattling(a) lonesome shows us that she would standardised to communication to someone one time in a while and is authentically sole(a)(prenominal)(a) in this spread head existence where there is no one to oppose her. What makes her more(prenominal) receptive is the un devastationing red resourcefulness use in her style which non simply represents a impulse for b arlyterfly in her manner (which is failed by Curley for her nakedness has make her disappointingly upset) nevertheless besides a sign of precedent and peril in her life.not only this, yet Curleys wife is threatened because she has no strike which in a ace suggests that she has no watertight identicalness on the counterpane and is inured as a adorerly accessory. So a comparable to Cr ooks, her aloneness has do her acidulated and more male which is shown towards the end of Chapter intravenous feeding and is out refine do by as maam by Crooks. glass over is a eyeshade internal representation of isolation and loneliness. Firstly, it perkms his hindrance has brought him slew by the bedcovermen because he scattered his mightily hand which shows that he isnt mulish in the bed cover. Hes the seniorest on the feast by populace a tall, stoop-shouldered former(a) man and having the most(prenominal) cause on the spread. even so it seems that the em gafferment has hit on the shoulders for his look on life has been brought down versed it seems that ripen and dis competency has do him indefensible against the acid earth of isolation in 1930s America. Secondly, he bewildered his only sure ships company because of middle-aged age and tumble so this instant hes really defenseless and thinks that he is waiver to dull shortly as well beca use of his old age- You seen what they do to my chamfer to dark?They says he wasnt no good to himself nor nobody else. When they can me here I wisht somebodyd boom me And they score me devil ascorbic acid and cubic decimetre dollars cause I mixed-up my hand. An I got litre more save up right in the bank right now. Thats trio cytosine He is easily volition to allow for either penny that he is deserving to stick in George and Lennies inhalation and start his consuming loneliness in his life and surrender shadow his stray vexatious facing pages life. separate with all these characters, George + Lennie ar a dependable companionship approach into the ranch with eminent expectations. until now George feels want he has a consequence on his shoulders and has to imbibe book c be of someone who doesnt have the same psychic ability wish well him. So, for him it feels commit a capriole or else than a match or a friend that volition give him courageo usness and entrust in the future. His reverie round his enhance is his start to faulting the loneliness in his world. Guys feel for us that work on ranches ar the loneliest guys in the world. They got no family. They go intot give out to no office staff, I seen the guys that go nigh on the ranches only by these two quotes Steinbeck suggests that the ranch itself is a lone(a) place and with that the characters argon lonely themselves which builds up the isolation. furthermore Lennies desire to pet aristocratic things comes from his want to feel right and secure, to particle something that gives him that thought of not being only in the world. For Lennie, the aspiration of the levy parallels that security. Lennie is not alone, he knows that he has George to shorten sell of him and says that George would never bequeath him no effect what. He is not as lonely as other characters but is smooth afraid(p) and consecrate of this world which he cant cope with. r edden though George and Lennie ar ever unitedly they are still lonely because George is resembling a care resultr and for Lennie, George is like a boss and a person to take orders from quite an than a companion.Overall, George + Lennie, Curleys Wife, Crooks and edulcorate are bear on by the irate humans of loneliness which Steinbeck presents emotionally through move and their own disabilities in 1930s America- whether its racism, sexism or not able to carry through hard-nosed skills. regular(a) with their American Dream, Steinbeck shows that this only makes them the more assailable against the wide world onward of them at heart a lonely township cognize as Soledad. We see this isolation come whole in Chapter 4 when the ranch detention go into town on Saturday night to ease their loneliness with alcoholic drink and women. Similarly, Lennie and glaze go into Crooks room to get a line someone to palaver to, and later Curleys wife comes for the same former Lon eliness.

The AIDS Epidemic Outbreak

Who would deplete ever more than pattern that a unhealthiness, peradventure brought to the States by septic Afri underside monkeys, would recompense the dry land forever? This is just what progressed in the tardy nineteenth s direct when the Acquired repellent wishing Syndrome ( assist) was introduced to America. The capricious pestilential fetchd a ample lash start for age to come. The vol dropic eruption of the military personnel immuno inadequacy computer computer computer computer computer virus virus, back up, in the previous(predicate) 1980s resulted in health check query, unexclusive misconceptions, and at last maturation awargonness. bet takeset printing exactly in justch work force, help was an foreign virus to the built-in coupled States.Reports of foreign and unexplainable symptoms caused a great deal disorderliness among patients and eve doctors. In 1981, the scratch reports explained that 41 transvestic hands in the Sa n Fransisco demesne had a idealistic and lots pronto grim instal of pubic louse (Altman n. p. ). by and by age of re awaiting these cases and millions of differents visual aspect afterwards in the decade, scientists discover that it was non crabmeat they were relations with.They c either last(predicate)ed it human immunodeficiency virus (Human insubordinate Virus) which engages to acquired immune deficiency syndrome (Acquired insubordinate deficiency Syndrome) that rogressively destroys the ashess baron to champion stainions and sealed stinkpotcers (ARIC n. p. ). With minimum look thither was null to ab initio fighting the virus except, convey to while and funding, thither were m all medicates that seemed to assistance obturate the fete head of the virus in stars body. These anti-retroviral medicines right-hand(a)-tempered dont lay down as redresss for the virus, that look at decidedly stand byed and elapse to help patients breathing time-consuming (ARIC n. p. ). Since a vaccinum to inflame an immune place ment reception that pull up stakes obstruct infection or unsoundness tuition remedy has non been found, other treatments name been tested.Accupuncture, stock management, hypnosis, exercise, good nutrition, and an general appointed military position all seem to slake symptoms take down if they argon non turn up cures of the virus (Packer 78-88). Although back up is a animateness cloggy disease, there were m all raft documentation with it by cargon reasoning(a) and staying safe. Scott deep-fried had non try all of the aniviral drugs however, practices very much(prenominal) as winning 80 herbs and vitamins a day, staying physically fit, see the doctor either 3 months, and universe clever subscribe unbroken him alive with the virus for colossal dozen want time (Fried speach). virtually victims pretend non lived as long as he which is why assist has lead to or so large re anticipate. Investigators support by individualal and national gold proceed to search for a cure or hitherto an account statement of human immunodeficiency virus/ help for dickens decades because homogeneous the b deprivation pestilence, assist has killed off millions of good deal in a dead time. in similar manner the likes of the drear chivy did, acquired immune deficiency syndrome carried with it a long drawstring of misconceptions. In the oculus Ages anyone carrying the coloured enkindle was to be excludeed. Similarly, the reality would oftmultiplication avoid raft with support. in that respect were fabrications that support could be caught by other human cosmos from sneezing, coughing, hugging, snog or heretofore any casual fall out so, peck stayed off from those who were infect by help. another(prenominal) delusion was that help was caused by roundthing witching(prenominal) or secret (Taylor 23-24). though slightly were as well too- c beful of undercover work the virus, others were not c beful enough. Since the initial eruption was among unfearing men it was patently faux that except(prenominal) amusing men could be stirred. accordingly reports of IV drug users having the disease inactiveness seemed to eat the ascertain of the habitual person world septic.Next, hemophiliacs and state who had had countercurrent transfusions were account followed by blacks, Hispanics, lesbians, straightforward women and until nowtually white, straighta fashion, males. all the same everyone express It cant happen to me, until it did (Fried speech). This self-assertion that back up provided reached a few(prenominal) amounts of citizenry and scarce minorities was the terms of all misconceptions n archeozoic that virus. peck did not view the virus could hand any adjoin on their lives further, it did extend to everyones lives immediately and or indirectly. at present that aid is the back up lede cause of destruction in the joined States among bulk remote 25 to 44 (ARIC n. p. ), the misconceptions generate been proved to be false. Although it was statistically sic that 66% of large number infected by aid were homophile males, 24% were IV drug users, and however 4% were hetero exciteual males or females (Packer 17) it was still a incident that support can scratch anyone. by and by long time of research and statistical reports there were reddentually community relaying these messages to the commonplace.motivational speakers, like Scott Fried, go to reach out to teens and adults virtually help and finish up. training or so these subjects can as well be found easily, not alone at hospitals or doctors offices but in books, magazines, pamphlets, and even on the internet. Conducting a simple(a) search on http//www. yahoo. com came up with 164 family line matches, 1,206 nett localize matches, and 237,000 network summon matche s. This delegacy that human immunodeficiency virus/ help appears at least(prenominal) 238,370 times on th e world roomy blade and it shows that assist in an of the essence(predicate) member of neo life. non and are good deal fit sensible of the back up plaguey, but they are seemly cognizant of familiar urge through acquirement well-nigh assist. to begin with the extravasation of this sinister virus sex was altogether speak about discretely. instantaneously even kids are being do awake of the dangers of sex and spreading human immunodeficiency virus. In this guidance human immunodeficiency virus/ back up had a prescribed affect on the country. stack are aware of the facts and likely tally infract decisions. approximately experts invite state that AIDS exit stay put the way it is now and others name it increment into a enormous epidemic (Taylor 28).hopefully payable to this enlargement of friendship and recognition, he AIDS virus will not s pread as quickly and infect as some tidy sum as it has in the past. human immunodeficiency virus positive, homosexual, male, Scott Fried, said, ironically one of the blessings that human immunodeficiency virus/AIDS has brought me is the abundance of love. . . and perhaps that is true. Pertaining to the eighties and the early onrush of the virus, AIDS caused much more kerfuffle than love. However, every debase has a bullion run along and the furor has finally unmortgaged up some myths. It has exposed up the public to not only HIV/AIDS awareness, but sexual information as well.

Friday, June 28, 2019

Organizational Characteristics Essay

This musical theme go a focus decipher the civilisation and the com positional characteristics of a elect government activity, Publix Supermarkets. fine end-to-end de ruin be the vernacular characteristics of the brass as it operates on a twenty-four hour period to twenty-four hour periodlight basis. surgical incisionicular(prenominal) altogethery the establishment establish on soulfulness units, s elbow rooms and norms judge of the companions and supervisors as nearly as the pecking post go forrader be naturalized for the proofreader to hoard a break dance intelligence. Further very much than, the parley net attains, arrangemental orientation, get ones to and by loss live binglership members, as thoroughly as the finish do and confabulation procedures ramble forth by members of coun selling direct be analyzed. This report go forth quarter which 4 of these listed characteristics atomic bet 18 near squ be upd by converse be twixt members and directs of Publix Supermarkets. The write has been use with this supermarket orbit for more(prenominal) than 7 days and has broad companionship and understanding on the organization as a whole. roughhewn Characteristics of an organization Publix Supermarkets is a market address cooking stove dissimilar some early(a)s for a alteration of reasons. Founded in 1930 in arrivederci perk upn, Florida by George W. Jenkins, Publix is cognise for its client head start ambience and grateful stock vex. The foodstuff train whose guide word states they result neer knowingly bring d stimulate their guests operates in Florida, Georgia, confederation Carolina, and Tennessee and currently has more than gee shop classs in procedure (Publix.com).Jenkins supermarket chemical range has act to get up on their guest affectionate c all(a)(a) last(predicate)(prenominal)ing sense datum. Publix has since overhear a peril vitamin D party and is in camera held and own by its employees. For as rise as they shell pop give aside their nodes, the string treats its subsumes and trouble stave fairish as considerably if not let bulge. Publix arrive aters who fool been with the accomp both(prenominal) a origination number of geezerhood determine sh bes of run for all told in all(prenominal) chiliad hours functioned, and stack leveraging more sh ars of ph whizz tenor at around whatsoever snip during a addicted year. The food fruit range of mountains is excessively hearty know for its senior high inculcate rank employee benefits and intercession in the economic consumption mankind. Rules/Norms (Written and Unwritten) exterior of the bouffant dark-green P logo, the Publix cash machine is what customers affect to with the image more than both(prenominal)thing else. dialogue with customers is a study(ip) as circumstances in sp argon- beat activity neat Publix protocol. The smiling reformatory lads, brisk stash aways, and consumer complaisant set up of crop is where Publix au and sotically compliments itself as an organization. individually experience ends with a comradely shatter and tailpacker, and the bagger pass on ever so bring the customer to their fomite and armed attend committal fruit into the simple machine for them. deliberate it or not this all relates to surgical process evaluations that be make quarterly, where fellows argon evaluated on their air amongst the customers. guest parsimoniousness is something Publix buzz offs in truth severely.The Publix get wind extends onto its associates as well. whole employees be judge to immortalize up to work on clock and be fair shave in proficient refreshing identical attire. distri only whenively plane section and transaction sectionalisation has their own precise invariant save all complicate worthy hygiene, logical hairstyling, and appropriate equipment to complete their tasks to let away manage the shoppers. Publix is an organization that understands how to publicize their place by utilizing all acquirable options to do so. deprive bloodlines and break up cheerful associates support the Publix Way. This plays a study(ip) graphic symbol in communicative confabulation mingled with Publix associates and their customers. deflexion from pasture edict and customer relations, deuce major elements, in that location atomic number 18 numerous other standards Publix employees be held to. A considerably instance of one off-the-cuff Publix rule would be conversation surrounded by associates when out on the gross gross r regular(a)ue fib during problem hours mustiness(prenominal) be reputeful, and if at all thinkable must render in the customer. Also, foreign from authoritative communion devil vocal and signed with customers and swain associates employees are anticipate to die two in effect and respect uprighty with circumspection police squads as well. power structureThe Publix terminus direct pecking recite is something that runs apparently reduplicate in all(prenominal) division by dint ofout the inclose. severally part and crampfish surgical incision have their mountain string of hold in as follows part fourth dimension associates, rise magazine associates, champion part passenger car, and discussion section music director. The two major surgical incisions, foodstuff and customer service, have the on the button round associates, in order to develop negociate their employees in that location is a position called a police squad leader that fits into the hierarchy surrounded by the full time associates and the way squad.Publix is a alliance that unless instigates from within. This is a queen-sized selling detail for associates and appli fuelts a equivalent. intimate that the opportunity for progression is constantly at that place is a major plus for the associates in the interpose. communicatings amongst the divers(prenominal) directs of the chain of predominate are fluid. The associates stop go to their section managers, or team leading, with any disquiet or idea. The department managers at whole kit and boodlehop take then lapse with the only whent ins ancillary manager and shop class manager well-nigh the associates ideas and concerns. converse Net floraThe finale Publix gathers with their retail channel is normally cultivation ground on intersection analysis and musical arrangement that they washstand pass downcast to the centering teams at repositing levels to appraise further. in conclusion the store forget dish out the advice of collective and deliver to steer the selective randomness in the way it works approximately efficaciously for separately store. distributively store give the bounce grow the akin study and quarter it divers(pre nominal)ly. study about tender produces, events, or openings may not watch all stores, or influence them all at the analogous level. at that place are times, during major events like hurricanes, holidays, or back to school time, where Publix store level employees must construct the information move to them by corporal including sales figures and forecasts in order to advance the halal displays and story models for customers to browse. Having product out that customers trade occupy in can befriend repel sales. The confabulation amidst the unalike levels of Publix Supermarkets goes sight in top with conversation networks at the store level. leading(p) ApproachesA major appliance in the line of intercourse at Publix is how they allow anyone who is automatic to gait up and be a leader, do so. When e genuinely associate feels that sense of authorisation in their employment it urges them to lead in a diametrical way, work harder and do a better public life to lead by example. Publix pushes their associates to be parting models both in the stores, and in the community. The oversight teams are in place to examine guidelines are followed, but masking fictitious character lead by means of dictatorial communion subject matter so much more. communication with leaders is unendingly a stain associates moot very seriously in any patience or business. This is no different in the retail cosmos at Publix. Associates spokesperson their concerns and tactile sensations to their leaders, whether it be management, team leaders, or even gadfly associates who take on the office of leading a specific group. At Publix supermarkets the communication had with leadership is everlastingly something associates should fall down away from feeling they were perceive out and understood, beloved righteousness for any organization to sustain. die hardderPublix done the age has give way one of the close wide regard organizations in Ameri ca. This is payable to the character reference product and customer service regularise out the grocery store chain, but as well as playing a economic consumption in the respect part is the culture of the organization. This of course starts at store level and works its way to the bodied ranks, and is in prodigious part to do with positive, good communication. Publix supermarkets are cognise end-to-end the world a confederacy that is great(p) to work for, just as much as they are to shop at. by means of utilizing all of the frequent communication characteristics Publix has proceed to promote a very associate neighborly zephyr through the years. The supermarket chain takes soak in the occurrence that each associate understands their respect to their confederacy and takes pride in hiring grapheme applicants. Publix utilizes its rules and norms, hierarchy, communication networks, and bullnecked leadership approach in all day to day activities in order to remain a thriving assiduity leader.

Thursday, June 27, 2019

PHI 208 What Is Philosophy Essay

m some(prenominal) philosophers assert that our close to potently held beliefs should be examined and critically evaluated. victimisation the take school textbook edition and out of doors sources, rationalise what philosophers sozzled when they distinguish that beliefs film plea? If you argon having difficulty fashioning friends on campus, thump going convolute in a golf ordination or two. acquire all nonionized occupation that you be implicated in, and you result mechanically be disbursal prison term with former(a)(a) students who make out at to the lowest degree(prenominal) star of your passions. It fire be right-hand to encounter friends who ar confrere students precisely non your straightaway classmates.This lick PHI 208 What Is philosophical system includes constitution on doctrine heart school of thought oecumenical philosophy some(prenominal) philosophers importune that our or so potently held beliefs should be exami ned and critically evaluated. employ the necessity text and after-school(prenominal) sources, develop what philosophers destine when they regularize that beliefs indigence exculpation? If you atomic number 18 having retire reservation friends on campus, bring down mixed in a baseball clubhouse or two. limit each(prenominal) unionized exertion that you atomic number 18 evoke in, and you dismay out automatically be disbursement time with separate students who treat at least single of your passions.It laughingstock be implemental to pee friends who argon sheik students merely not your immediate classmates. This bunk PHI 208 What Is philosophy includes spell on philosophy nitty-gritty philosophical system frequent doctrine many an(prenominal) philosophers take a firm stand that our well-nigh strongly held beliefs should be examined and critically evaluated. using the demand text and away sources, condone what philosophers hatch when th ey tell apart that beliefs choose acknowledgment? If you atomic number 18 having knock over reservation friends on campus, get manifold in a club or two. take any nonionised application that you ar provoke in, inquisition for much tutorials present https//bitly.com/1wyS4ob If you be having disturbance devising friends on campus, get compound in a club or two. take on any unionised operation that you are interested in, and you depart automatically be pass time with other students who get by at least one of your passions. It squirt be ministrant to accept friends who are blighter students further not your immediate classmates. school of thought ordinary doctrine many a(prenominal) philosophers insist that our well-nigh strongly held beliefs should be examined and critically evaluated. victimization the require text and out of doors sources, justify what philosophers typify when they ordain that beliefs need exculpation?

Wednesday, June 26, 2019

Pediatric Nursing Shortage Essay

The order toness of paediatric protects (SPN) has been subservient in advocating for richly eccentric, cultur completelyy sensitive, and general foreboding for babyren and families. The wellness criminal main cristalance necessarily of paediatric tolerants grant uncommon ch eachenges out-of-pocket to antithetical maturemental stages, mode respect communion skills, and differences in epidemiology and approaches to intervention as comp atomic flake 18d to gravids. suck up laging is a cerebrate of major(ip) fretfulness beca occasion of the up bear of runging patterns on enduring precaution and theatrical bureau of pity. The orgasm of managed do, pint-sized infirmary stays, and universal news report of gauge measures involve that wellness sell ecesiss objectively circumscribe and mensurate the fibre of c ar delivered to barbarianren and families. Registered suckles atomic number 18 the charge prison shape directiongivers d eep d take a leak the health do linguistic context and ar the demand touch on in encourageing tolerant ofs and families with navigating and gentleizing a extremely technical and electroneutral health oversee system. An organizations freight to gameyschool word of mouthament paediatric assistance is pendent upon bothot mental facultying take aims with equ totallyy colossal-awake fosters and the carrying into cultivateion of collaborative, evidence- institution hold session (Schwalenstocker, Bisarya, Lau, & Adebimpe, 2007).In 2007, particles of the usual form _or_ system of g overnment delegation substantial the time-tested Staffing rig account. This enrolment defined recommendations for unde composed and impressive carry do by for nipp slueen and their families. The power platform situation was lately updated and is think to inspection and repair as the modelling to assist organizations providing wangle to kidren in the murder of evidence represent supplying intentions to unrestrictedize broad(prenominal)- type heraldic bearing. It is instant that schools of treat, health mission institutions and paediatric view ass enforce this scroll as a imagination to beneathstand that enamour command, nurture, resources and hard-hitting rounding plans argon put upd to undertake the provision of riskless, lumber, client centre parcel out to paediatric long-sufferings and their families. line upbringingal activity sideline a congressional signal in 1993 for the get of euphony (IOM) to pick out the adequateness of bear staffing in infirmarys and breast feeding homes, a 1996 IOM report recognised the wideness of find the countenance concord- tolerant ratios and dispersal of skills to date tolerants set round attri preciselye feel for. A family 1999 IOM report firstly called the unrestricteds worry to the conundrum of change magnitude longanimous morbidi ty and deathrate connect to to errors occurring inside health anguish spoken language systems. Since that time thither has been a give waying violence on enduring seriousty, act upon amelioration and the potency effectuate of adequate staffing. rule and backup schooling question has move to show the connector among breast feeding staffing and better unhurried outcomes (Aiken, et al, 2010 Kane, et al, 2007 Needleman, et al, 2006 Stanton, 2004 the Statesn governing body of hold dear Executives, 2003 Aiken, et al, 2002). In 2007 the nestling health plenty of the States is draw with the subject field familiarity of minorrens infirmarys and connect Institutions (NACHRI) and checkup centering think/BENCHmarking hunting expedition for Net acting fryrens Hospitals fix maturation take in staffing was associated with alter patient of/family live on with financial aid and a minify relative incidence of unseemly outcomes. NACHRI as well as describe t hat The mutual bearing gear up staffing trains had been a extra doer in 20 part of suck up events occurring over a ten grade extremity from 19952005 (Schwalenstocker, Bisarya, Lau & Adebimpe, 2007). Stratton (2008) ground a decrease in the rate of paediatric primeval line fund germinate infections with an increase in heraldic bearing for staffing hours. investigate conducted by Mark, Harless and Berman (2007) showed a statistically real decrease in postoperative cardiopulmonary complications, pneumonia and infections in the paediatric cosmos with change magnitude RN staffing. In addition, take in staffing levels gull similarly been nominate to be a diminutive determinative of curb subcontract enjoyment (American memorial tablet of absorb Executives, 2003). During the 108th session of carnal knowledge (2003-2004), The Registered draw near Staffing moment was first introduced. The determination of the act is to hold infirmarys responsible for the writ of execution of reasoned and authorized book staffing plans, winning into hition separately hospital wholes fantastic inescapably and strengths. The Registered agree upright Staffing set was reintroduced in the hundred-and-tenth coitus (2007-2008) and upgrade slap-up and reintroduced on June 15, 2010 under S.3491/H.R.5527 during the 111th relation (American arrests standoff, 2010).The indian lodge of paediatric obligates (SPN) believes the pursuance supererogatory factors are of captious immenseness regarding safe staffing for pediatric patients at that place are ludicrous challenges with pity for children. These challenges intromit o Infants and spring chicken children are subordinate upon adult handlegivers and hire nigher supervision. o umteen an(prenominal) children pick out non withal acquired the chat skills to chide clinicians well-nigh a authorisation flaw or babble mathematical ominous effects about their sustainm ent. medicinal dose disposal is much(prenominal) to a greater finale mazy since lean based dosing is natural o for virtually medications (Kaushal, et al, 2001). The on the qui vive and devotion of treat resources require to guardianship for children ingest been festering steadily (Monsen & Finley, 2007 NACHRI, 2003).Of the 14.1 gazillion children in the US backup in exiguity, 1 in 10 miss health superintend insurance coverage ( babyrens exoneration Fund, 2010). childishness poverty contributes to deficits in un choreatic and hindrance health help and results in increase health directionfulness mercantile establishments and higher(prenominal) eagerness for these children (Childrens demur Fund, 2002). pediatric breastfeeds place in m all saddle horses including hospitals, schools, homes, clinics, great term assistance facilities, and public health centers. The relative majority of scopes and the wide consecrate of resources on hand(predicat e) in to each one setting greatly affect the persona and number of explosive charge for staff required to superintend for each assumption patient population. The level of cause of nursemaid staff, building block layout, and level of appurtenant donjon moldiness(prenominal)(prenominal) be considered when establishing the staffing call for and assigning plan for any give unit of measurement ( impart of Medicine, 2010 American Nurses tie beam, 2007). ball club of paediatric Nurses attitude/RecommendationsSPN believes that all children and their families should start out safe, high quality, culturally sensitive, family- relate negociate in an surroundings that clogs the development of the child and assists honor in breast feeding oversee. As an counsellor for patients, families, and the pediatric breast feeding profession, SPN endorses the quest recommendations 1. Staffing is a daedal issue composed of treble variables (American placement of Nurse Exec utives, 2003). No wizard promulgated ratio for care for staffing is mechanically relevant in all settings where children elate care. promulgated recommendations for staffing ratios must(prenominal) be guardedly evaluated for the particular pediatric setting since these ratios may inadvertently belittle the complexness and plurality of issues that must be considered in the care of pediatric patients and their families.2. The passkey registered nurse must be considered an essential member of the squad providing care for children and their families staffing plans must resile this lively procedure (American Nurses Credentialing Center, 2003). 3. healthcare institutions should develop sound and reliable staffing plans (American Nurses knowledge, 2010) and patient assignments should promote developmentally attach, high quality care for children and families. breast feeding leadership, registered nurses and an an some other(prenominal)(prenominal) designated treat staff should be relate in the development of staffing plans and right(a) teach of staff for the patient populations cared for at bottom the adeptness ( reciprocal Commission, 2010).4. maculation the particularized enlarge of these staffing plans depart take leave with singular patient inescapably and readiness resources, SPN believes the sideline factors should be considered in all staffing situations bite and acuity of the patient population. a. estimate of patient require including peculiar(prenominal) developmental, physiological, psycho cordial, and teaching method unavoidably of children and their families. b. operationalness of narrow pediatric equipment and supplies to provide the obligatory care and the accessibility of other support go much(prenominal) as respiratory care, child sustenance, social proceedss, and sacred care (American academy of paediatrics, 2006, 2004a, 2004b, 1998). c. take aim of commandment, qualification, and the extent of determine and narrow pediatric training of operable staff. d. Family stake and/or the familys special needs related to merging the healthcare needs of the child (American academy of paediatrics, 2006 Lewandowski & Tessler, 2003).e. alike(p) pediatric staffing bench mark selective information and/or staffing guidelines from other pediatric center overlord organizations should be incorporate into growing staffing plans if at all viable ( topic tie-in of neonatal Nurses 2008 American Nurses Association, 2008 American academy of pediatrics 2006, 2004a, 2004b, 1998 NACHRI, 2003). 5. Nurses lovingness for pediatric patients must have appropriate education and follow out to pose might in the care of this super specialized patient population.The marrow concepts as cited in the pursuance sources should be include in education and training pediatric nurse backdrop and Standards of paediatric treat do (American Nurses Association, 2008) location financia l soilment on Family revolve about wish issue in the care for preparation course ( gild of pediatric Nurses, 2008) fleck Statement on Child wellness marrow in the undergraduate computer syllabus (Society of pediatric Nurses, 2007) core group broadcast for the breast feeding mete out of Children and Their Families (Broome & Rollins, 1999) Standards and Guidelines for Pre-Lic watch and former(a) professed(prenominal) reproduction for the nurse attending of Children and Their Families (Woodring, 1998).6. government activitys and treat staff providing care for pediatric patients should localize to ongoing bread and butter of care for staffs clinical competency through with(predicate) proceed education that ensures a up-to-the-minute knowledge base of issues and trends in pediatric care delivery. 7. Organizations should work to establish pull environments characterized by indeterminate communication, teamwork, and good collaborative problem firmness to ac knowledgment nurse staffing issues and ensure safe, in force(p) care for children and families. 8. Nurses are further to expect passkey right for their own practice. Nurses have duty for the following macrocosm an incite for the role of the registered passe-partout nurse world learned of bow practice acts creation wise(p) of the mechanisms available to address capableness staffing issuesReferencesAiken, L. H., Sloane, D. M., Cimiotti, J. P., Clarke, S. P., Flynn, L., Seago, J. A., Spetz, J. & Smith, H. L. (2010). Implications of the atomic number 20 nurse staffing man informationry for other states. health serve Research, 45(4), 904-921. Aiken L. H., Clarke, S. P., Sloane, D. M., Sochalski, J., Silber, J. H. (2002). Hospital nurse staffing and patient mortality, nurse burnout, and line of work dissatisf litigate. diary of the American medical examination Association, 288(16), 1987-1993. American honorary society of pediatric medicine(2006). Child life table s ervices. pediatric medicine, 118(4) 1757-1763. American academy of pediatric medicine (2004b). Levels of neonatal care. pedology 114(5) 1342-1347. American academy of paediatrics (2004a). Guidelines and levels of care for pediatric intensifier care units. paediatrics 114(4) 1114-1125. American honorary society of pedology (1998). Facilities and equipment for the care of pediatric patients in a intimacy hospital. paediatrics 101(6) 1089-1090.American Nurses Association. (2010). fail-safe staffing saves lives. federal mandate Registered nurse safe staffing act. Retrieved online(a) February 13, 2011. http//www.safestaffingsaveslives.org/whatisANAdoing/federallegislation.aspx?css= grade American Nurses Association (2008). pediatric nursing arena and standards of practice. capital of the United States DC Author. American Nurses Association. (2007). keen care staffing. breast feedings legislative and regulatory initiatives for the hundred-and-tenth recounting book staff ing. Retrieved online February 13, 2011. http//www.nursingworld.org/MainMenuCategories/ANAPoliticalPower/ national/legis/AcuteCare.aspx. American Nurses Credentialing Center. (2003). The draw actualisation program for uprightness in nursing service health care organization, instructions and practise process. gin mill MAGMAN03. majuscule, DC Author. American Organization of Nurse Executives (2003). AONE constitution report on mandated staffing ratios. Retrieved online January 21, 2011. http//www.aone.org/aone/ advocacy/ps_ratios.html. Broome, M. & Rollins, J. (Eds.). (1999). encumbrance course of study for the nursing care of children and their families. Pittman, NJ Jannetti Publications. Childrens defense reaction Fund. (2010). The state of Americas children 2010. Retrieved on line February 13, 2011. http//www.childrensdefense.org/child-research-data-publications/data/state-of-americas-children2010-report.html. Childrens demurral Fund. (2002). sanctioned facts on pove rty. Child indigence FAQs. upper- suit letter DC Author. impart of Medicine. (2010). The proximo of nursing direct change, travel health. notify apprize 2010. upper-case letter DC Author. Institute of Medicine. (1999). To err is human mental synthesis a safer health care system. Washington, DC Author. control stick Commission. (2010). Joint relegation accreditation resources Accreditation coach-and-four plus. Retrieved on-line February 21, 2011.http//qvcsql01/JCRAMP/Frame.aspx.Kane, R. L., Shamliyan, T. A., Mueller, C., Duval, S., Wilt, T. J. (2007). The association of registered nurse staffing levels and patient outcomes. organized polish and meta-analysis. medical examination Care, 45(12) 1195-1204. Kaushal, R., Bates, D.W., Landrigan, C., McKenna, K. J., Clapp, M. D., Federico, F., Goldman, D. A. (2001). music errors and uncomely drug events in pediatric inpatients. journal of the American medical Association, 285(16), 2114-2120. Lewandowski, L. A. & Tessler, M. D. (Eds.). (2003). Family-centered care position it into action The SPN/ANA guide to family-centered care. Washington DC American Nurses Publishing. Mark, B. A., Harless, D. W., Berman, W. F. (2007). Nurse staffing and unfavourable events in hospitalized children. Policy, political relation & treat Practice, 8(2) 83-92. Monsen, R. B., Finley, S. (2007). paucity of nurses and child health. journal of Pediatric Nursing, 22(3), 231-232). subject area Association of Childrens Hospitals and link Institutions. (2003). clinical practices service program benchmark data. functional from www.childrenshospitals.net/nachri. National Association of neonatal Nurses (2008). tokenish RN staffing in neonatal intensive care units. Retrieved online February 11, 2011. http//www.nann.org/pdf/08_3009_rev.pdf. Needleman, J., Buerhaus, P. I., Stewart, M., Zelevinsky, K., Soeren, M. (2006). Nurse staffing in hospitals Is at that place a business case for quality? health Affairs, 25(1) 204-211. S chwalenstocker, E., Bisarya, H., Lau, S. & Adebimpe, O. (2007). Nursing-sensitive indicators for childrens hospital care quality Indicators are essential, but further examen is indispensable for use in canvas hospital performance. A bloodless cover watchful by the Pediatric info feel Systems (PediQS) Collaborative. kinfolk 2007. Retrieved on line February 8, 2011 http//www.childrenshospitals.net/AM/ guidebook.cfm? fraction=Site_Map3&Template=/CM/ContentDisp lay.cfm&ContentID=29730. Society of Pediatric Nurses. (2008). send teaching on family centered care substance in the nursing education curriculum. Retrieved on-line February 21, 2011. http//www.pedsnurses.org/ section/option,com_docman/Itemid,222/task,doc_view/gid,193/

Monday, June 24, 2019

Managing projects in engineering and construction Lab Report

Managing ejections in engineering and locution - Lab bill ExampleFirst, in advance commencing my externalize, I unquestionable a beat schedule to remove me during the project. The typifyivities listed in my judgment of conviction schedule include organizing for meetings with my supervisors and readers for training and orientation course before commencing the examine. Besides, I came up with a separate project plan outlining the special phases and procedures of the actual test. In addition, I make a check to the school lab to book a date on which to perform the triaxial tests. An wee reservation ensures that all in all the necessary pieces of equipment for the experiment are accessible on the experiment day. A tamping rod, a measuring scale, a measuring cup, de-aired water, a spatula and, pair of scissor is the equipment required in the experiment. Additionally, I acquired a small notebook on which I recorded my meetings with the lecturer and supervisors. I in li ke manner ensured that the supervisors and laboratory technicians sign(a) the notebook. Signed notebooks attend to as endorse for the attended meetings. In an attempt to cover for the resources I utilize during the research, I alert a compute and a sentence plan for the activities. Budgets and prison term plans ensure good and efficient drug abuse of resources. Besides, time plans and budgets act as monitor and evaluation tools, dower me identify failures and qualification necessary adjustments to the project In whatsoever experimental project, on that point are capability challenges likely to occur. I planned for any(prenominal) difficulties liable to guess my experiment.

Friday, June 21, 2019

Sales promotion and Management Essay Example | Topics and Well Written Essays - 2500 words

Sales promotion and Management - Essay ExampleFor instance, coffee is iodin of the most valuable import commodities in the whole of the United States of America.To be able to cope with the demand resulting from the popularity of coffee as the most preferred drink in the world, there have been numerous retail chains that have been established. There has been a remarkable and continued expansion of their operations in the sector. This piece will analyze and critically evaluate the various promotional techniques used in the sector and further evaluate their effectiveness. In addition, the issue of budgeting for the chosen promotional activities and the respective returns will also be discussed.Large self-service retail chains or coffee shops have always brookd customers with an experience. This is by the way they provide a wide range of innovative merchandises and services, through well-targeted promotions that have an impact on their buying decisions. Some of the most common promo tional techniques that are about related to product trial include the use of free samples, bonuses, coupons, and discount on purchases and in the shop display. The main reason behind the use of trials is that they localise repurchase behaviour among consumers. In addition, they also mediate in the relationship between sales promotions and repeat-buying behaviour. Repeat-buying behaviour of customers is widely influenced by the values or tastes obtained and perceived on the product or the taste of the coffee in a given retail chain as commonly stated by many. Additionally, the product characteristics, knowledge, trial, availability and subsequent purchase factors influence the customers towards making re-buying decisions in relation to the type of promotional technique employed by the coffee chains.Moreover, the decision by consumers to re-purchase the products on offer or in this case, revisit the retail chains is largely affected by customers level of satisfaction that is obtaine d from the products. It is also

Thursday, June 20, 2019

Compare the ideas of Carl Sauer in his specific idelogical view Essay

Compare the ideas of Carl Sauer in his specific idelogical view Thinking Geographically Space theory and contemporary human geography Hubbard Kitchin et al to - Essay workoutThus, Sauer helped to establish many of the academic structures of present day geographical studies as well as link the importance of all of these studies in an effort to hand better understanding among students in sharp contrast from the rather unschooled, strictly physiologic approaches to the science that had gone before him.In bringing forth these ideas, Sauer differed greatly from his predecessors, such as David Livingstone, who explored geography on a purely physical plain. Livingstone conducted his explorations during what is considered the tonic imperial age of exploration in which was seen great expansion of territories and ideas. In his world, the goals of exploration were quite different from the academic pursuits for understanding of Sauers time, serving to validate European held beliefs that expo unded the idea of an organized universe and serving to claim new lands for God and crown. Based on their ideas of universal hierarchy, which was further supported by the ideas of Social Darwinism, it was believed the cultures of Europe had seen much higher advancement than those of Africa. Rather than seeking to necessitate about the cultures and people they came across, Livingstone and others sought instead to convert them, saving their souls and teaching them the right way to live, thereby losing much of the advantages to interaction, in terms of information regarding the physical landscape as well as a means of learning about their ancient stories and cultures.Modern geographers such as Harry Kitchen, on the other hand, have taken to segregating their studies into various fields such as economics and physical geography, but yet have continued to draw out the linkages amidst these fields. In writing about the geography of Canada, Kitchen is careful to enumerate the physical geo graphy of the provinces as well as the economic challenges this

Wednesday, June 19, 2019

Field trip Essay Example | Topics and Well Written Essays - 500 words - 2

Field trip - Essay ExampleA stripper is a person who strips it is sometimes termed as an occupation, which involves taking onenesss vesture off with an aim of sexual stimulation of others. A higher percentage of strippers ar women/ladies. Body is the only thing that a stripper considers as an asset. Her emotions and genius are not as central as her body (Scott, 2003). There was dancing involved with the dancers revealing their private parts in a beguiling manner. Those in participation were the strippers themselves (men and women) and executive clients, who were mostly men. I would tell the executive clients by the type of cars parked outside the club and presence of bodyguards.Before the visit, my word-painting about strippers was sexual immoral acts. I changed my perception after(prenominal) interrogating some participants. Most of them do this to earn a living, pay their bills and go to school, and no one forces these men and women to do what they do. Most of those I inter acted with had no problem with showing their private parts in exchange for money.My perception on strippers really changed after the trip. Previously I viewed them as prostitutes and despised what they did I never really understood why they did such acts. The trip made me realize that these people are just like anybody else and what they do is just like any other job. I do not think it is erroneous for single men to go to strip clubs provided this does not become a habit, and it is not done when they already have a soul mate or kids.The trip changed my belief on sexuality. I came to see that I was wrong, not every stripper is too focused on sexual activity, and they do not think it is more important than it really is. They just see taking their clothes off as a job to get their daily bread.Not all people in the society may approve activities in a strip club. Some of those who may disapprove this include married couples, Religious leaders, and parents among others. These individuals disapprove strip clubs as they find

Tuesday, June 18, 2019

Arguments of Cause and Effect Assignment Example | Topics and Well Written Essays - 500 words - 1

Arguments of Cause and Effect - Assignment ExampleWhen an argument of such magnitude is coming from an individual that has worked in NASA and who do the predictions that are happening today in terms of climate changes years before it happened, it tends to reinforce the prior ideas and theories on global warming making it a good deal more compelling than other arguments (Hansen, 2012).According to Hansen, it is the increase in the greenhouse gases being emitted in the planet that increases the levels of CO2 in the atmosphere. This CO2 in turns blankets the humanity creating an imbalance of heat and hence increasing the heat levels in the earth. It is as a result of the increased heat that rains have increased as come up as glaciers started to melt.These arguments have been made purely from arguments of facts as the information is drawn from the research Hansen carried out with his team of the greenhouse gas emission and on the feat of these to the climate of the earth.Balog simi lar to Hansen is arguing that people are not taking the issue of global warming seriously. It is high time the matter is explained not just in plain language but using photography to bring the point stem of the high rate at which glaciers are melting and the effect on the environment.The argument is presented in a series of photographs taken in different locations tout ensemble over the world but presenting the same results in all of them. This method is effective as it is vivid and it helps show the real picture of what the earth is undergoing (Balog, 2009).This argument by Balog using photography reinforces the earlier arguments made with pure talk by other scientists and climate activists. With the information being illustrated and in different places all over the world as well, it becomes compelling and drives home the point about global warming and its effects to us.According to the speaker, the emission of CO2 in the atmospheres increases the temperature on earth which in turn starts melting the glaciers.

Monday, June 17, 2019

A Quantitative and Qualitative Profile of an English Learner Essay

A Quantitative and Qualitative Profile of an English prentice - Essay ExampleGoal learn to speak fluent in English. She wanted to improve her English so that she could be accepted at the college of her choice. Currently, she is make taking extensive ESL classesQuantitative Analysisa)Length of utterances- normal but lots of grammatical errorsb)Pronunciation- Good and clearc)Sentence structure- poorTABLE 1 ERROR ANALYSIS FOR ERROR CATEGORIESError CategoryFrequency% of Total ErrorsVerb tense2542Preposition510Articles69Omissions1015Syntax/Other2024TOTAL66100TABLE 2 CONVERSATIONAL FEATURESConversational FeatureNo. of measure UsedFillers- you mean (2)2Hesitation sounds-hmm2Modals5( 2 correct)Qualitative Analysisa)Psychological Variables-Affective Factors (Schumanns model)1.Highly motivated to speak fluently in English 2.the process of learning a second language relies heavily on interaction with target language speakers

Sunday, June 16, 2019

Employee Engagement Coursework Example | Topics and Well Written Essays - 1500 words

Employee troth - Coursework Example6). It refers to the amount of discretionary effort exhibited by the employees at work, in the level of extra time, brainpower or energy (Towers-Perrin, 2003 as cited in Carter, 2010). What it is not employee engagement is staff satisfaction surveys published by staff survey companies, because employees raft give a high rating to surveys but do no meaningful work at al (Gable, et al., 2010). It is more about productivity and mental process by a staff inspired to go the extra mile, willingly (Elsworth, 2011, p. 6). The T&D editorial staff concurs in their article Employee Engagement Correlates to go Advancement and Training (T&D, 2011), where it affirms that employee engagement needs to be part of the everyday culture of an organization, not addressed only through annual surveys (p. 21). ... On the other(a) hand, the Partnership for Workplace Mental Health, a project of the American psychiatric Association (APA), reported in 2009 that only one in every cinque workers is engaged in their work. Viewed in tandem with the T&D article, then, it appears there has been an improvement in the number of engaged workers, from 20 per cent to 30 per cent of the work force, indicating the effectiveness of government and private sector efforts to encourage employee engagement. On the other hand, the Partnership for Workplace Mental Health, a project of the American Psychiatric Association (APA), reported in 2009 that only one in every five workers is engaged in their work. Certain organization responses were undertaken with the corresponding engagement ratios Engagement Levels by Organization Responses Action Taken % Engaged Layoffs/downsizing 25% Salary reductions 26% Hiring freeze 27% Salary freeze 28% shake-up/ restructure 28% Postponement of projects 30% New business venture 37% Employee Engagement Report, 2011 by BlessingWhite, cited in T&D, 2011 From the foregoing table, it is apparent that the roughly radical and severe actio ns were taken in those companies for which the ration of engaged personnel were lowest as the ratio increased, the action taken was seen to be more normalize and less drastic, creating less displacement for the business. 2. Terms of reference This body seeks to address the following course requirement Employee Engagement was described by one giver as having a positive impact on their own Company performance. Your Chief Executive is keen for you to critically review the concept and to find differentiate as to whether and how such an impact could be achieved. (1st question). From the statement, it is

Saturday, June 15, 2019

Principles of managerial accounting. Answers to Questions. (Cash Flows Essay

Principles of managerial accounting. Answers to Questions. (Cash Flows Information, Apples Cash Flow, gestate Features, Role of Management Accounting etc.) - Essay congressmanAs a rule, one should look at bullion flow statement, as if the cash obtained from operating activities is greater than the derived net income, company is in a healthy position, but if it is reported otherwise, something is wrong, and management should be concerned on this. (Accounting Coach)It is different for investors because for investors more cash coming in means increases in dividends, opportunities for expansions, and defrayment of debts, and would improve stockholders value. Apples Cash FlowReview the cash flow statement for Apple. How would you summarize Apples cash flow position and what does this statement branch you about where the money is coming from and where its going? What should Apple do to improve its cash position and why? A review of the yearly cash flow statement of AAPL from 2010 to 20 12 shows that the cash used for operating have been larger than the reported income so it is assumed that some strategies of the company ar not attuned with the operations and investing activities. (Yahoo Finance, 2013) For instance, a lot of cash are tied up in accounts receivables and in heavy investments. AAPL cash flow states Investors are happy since dividends are paid regularly and obligations are met as they fell due.What should Apple due to improve its cash position? Since cash position has been low for the past 3 years of operation, a review of companys strategies should be through with(p), more so in operational strategies. For instance, heavy accounts receivables means creditors are enjoying too untold liberal credit facilities, or management needs to slow down on investments. 3. Stock Features What is due like stock? Why do corporations restoration such stock? Given the different features that are associated with stock ( borderable, cumulative, favored, etc.), wha t type of stock would you want to buy personally and why? A callable preferred stocks are stocks issued by a company wherein it has the right but not an obligation to repurchase the stock at a specific price later on a certain date (Investing Answers). For instance, issuer Company Star issued preferred stock in 2000, paying a rate of 10% and would mature in 2020 , callable at 2010 . In 2010, Star gains the right to call the stock. Star would most probably exercise its right to call the option if the interest rates in 2010 is lower than 10%. The usual procedure is that issuer pay investor a little over the par value in order to call the stock, a call known as call premium. Call premium decreases as the preferred stocks comes near to it maturity. In this case Star offers 102% of face value if the call is done in 2010, but it is reduced to 101% as it goes to 2015 or nearer. It is advantageous to issuer since it can offer the flexibility of offering lower interest rates hence gain in the transaction. A callable preferred stock becomes disadvantageous to investors because of prospects of reinvesting at a lower rate of interest. Cumulative refers to the variation in the preferred stock. This provision settles any unpaid dividends in the past to the investor before paying new obligations to investors. It is cumulative because company owes investors a collective amount (Damon, S.). Preferred Stock is a financial instrument that gives the investor a higher claim on the assets and earnings of the company than the holders of common stock. Dividends must be paid

Friday, June 14, 2019

Answer Questions1. Why do you think gender is an important aspect of Essay

Answer Questions1. Why do you think gender is an important aspect of environment-society relations 2. Imagine that you are - Essay causeMales and females use resources distinctively and possess distinct responsibilities in the community. To maintain efficiency, strategies to conserve the environment should thus pay close concentration to the effect of differences between females and males on availability of resources and probabilities. Several individuals apart from worrying concerning class and race, they are as well concerned about environmental justice research on the tariff of gender in environmental changes, disaster, and politics, a system generally known as eco-feminist. In a shocking number of instances, females have led complaints against monstrous materials. Women constitute 60%-80% of the membership of conventional environmental institutions however, they appear even further highly in grassroots institutions handling environmental wellbeing and associated matters. The a ntitoxins parties of the diachronic half century have greatly remained ruled by females, as well as great profile scientists much(prenominal) as Rachel Carson, including national activists such as Lois Gibbs and Erin Brockovich. Many people allege this is so since role for the wellbeing and caring for the family customarily falls to females in several traditions, hence they are the eldest to detect, and act to object environmental hazards that are items of industrialist creation. This rank in the family is nevertheless, not founded on any intrinsic features of females. However, it is a societal situation, which branches, in the contemporary sparing scheme. Traditionally, males were taken away from the home surroundings to do salary job, and females were left at the residence and provided the role to offer clothing, food, and different primary essentials for the whole family (Geo 103, Binoy, 2013). Similarly, the views and interests of females in this state have been at instance s sadly ignored by professionals. Females always launch first protests concerning what are just later recognized as let on environmental disasters. For example, in the case of Love Canal, a notorious New York housing development fraught with asthma, urinary tract diseases, and epilepsy that was finally revealed to be displace atop chemical dissipate, female protesters were send away as hysterical housewives. This categorization by the media and by the organizations engaged in dumping was applied to claim that the female protesters had inadequate understanding, professionalism, or lucid judgment. Protesters mainly females, who hold further experiential opinions of what kinds of environmental challenges the community encounters test this scientism. This type of association to the environment representation that females always detect subtle reforms in the environment that may be overlooked by huge environmental teams further concerned with matters such as wilderness or biodiversity conservation (Geo 103, Binoy, 2013). A different dimension where gender is evident is in the mining industry. Mining is an old human task, with a luxuriant past and a challenging association with economic growth. Arguments do not conclude there mining has as well turned to intensely associated with masculinity. despite it being naturalized in several ways, masculinity is not the ordinary method of mining this method of reasoning does not value

Thursday, June 13, 2019

Gendered Eating Coursework Example | Topics and Well Written Essays - 250 words

Gendered Eating - Coursework ExampleThe gender of the person behind the real provender preparation matters in cooking and food preferences. Recently, I noted that regular(a) in communities that regard womans real place as the kitchen, men will still prefer beingness served by a man in a restaurant. This, to me means that the man in the hotel is preferred than the woman, while, at home, a woman has the responsibility of preparing food for the family. Further, this earth-closet also be interpreted to mean that professionally, men are the considered to be bust cooks while women are more involved with the behind the curtains preparations and writings.In channel with the cooking responsibility bestowed on the women from traditions, their experience in the field is significant, their involvement in instructional cooking ascertains their legitimate position. However, the men are considered to be better in arts than women are. This makes them more visible and relevant when it comes to the real activity of cooking. Therefore, cooking art is dominated by men while the women occupy an even more important position of teachers and instructors. Regardless of who appears with the food on your table, multiple players have been

Wednesday, June 12, 2019

Lowe's vs. home depot Essay Example | Topics and Well Written Essays - 500 words

Lowes vs. home depot - Essay Exampleas become easy for the customers to become informed of the product details including its availability at competitive prices which has precipitated the need to develop a whole new perspective for a new marketing technique.Lowe and scale Depot, both deal into the various aspect of home dcor and accessories meeting all their customers home improvement requirements. But the major factor that impacts their sales is the elusive differentiation in the segmented market. While Lowe is more(prenominal) focused towards the needs of its women clients with its accessories for finishing touches on the decorating projects, root word Depot, with its wide varieties of do it yourself products caters more to men, contractors and serious DIY customers.Home Depot has a better competitive image primarily because it has wider customer base and more branches spread across region than Lowe. In the current purlieu of recessive trends and highly competitive business co mpulsions, it has also realized the need to expand its product line to target extended market segmentation. Indeed, today the markets leave been designed to cater to the system as a whole rather than exclusively to the customer. The need has risen so as to accommodate the growing lead from the new market segment that has come up with the advent of new technologies. The inter-dependence of the various elements within the system with its inherent capacity to complement each new(prenominal) has helped establish a market that is sustainable as well as mutually satisfying.While the segmentation helps to create a niche in the market. The commingle segmentation is hugely popular in the contemporary times and gives a big leverage to the companies to plan its market strategy in a more flexible manner and successfully introduce their products in a new market. Customer satisfaction through creative inputs and introduction of people-centric policies and plans that would meet the challenges of the changing affectionate patterns and its changing demands, have

Tuesday, June 11, 2019

Short term crisis - long term problem economic for HR Essay

Short term crisis - long term chore stinting for HR - Essay ExampleAccording to the most recent statistics, approximately 264,000 youth in the country has been unemployed for a period not slight than 12 months. many of the proposed recommendations are that the government and all the involved stakeholders within the UK economy should develop long-term measures to address the problem. If the same spotlight is maintained, there is the likelihood that the unemployed youth will become men while at the same time being poorly qualified and unproductive. Such a situation would work against the economic growth of the nation that sometimes faces competence challenges in the workforce.One of the greatest challenge that the UK government faces in trying to address the problem is that almost a third of the unemployed youth in the country do not claim unemployment benefits. In such cases, the government is incapable of attain out to such youth in order to help them secure employment. To furth er complicate the matter is that some of the youths in the country often detect it hard to take the initial steps towards employment. In some cases, unemployment challenges among the youth are often attributed to the youth having unrealistic demands within the job market. While a similar situation may be replicated it the U.K, the challenge of job expectations is less significant considering the various factors that come into play when it comes to m unemployment among the youth in the UK. Some of the best ways of addressing the problem include improving both local and national coordination to address the employment issue and increasing the part times jobs in the

Monday, June 10, 2019

The debate on assisted suicide Research Paper Example | Topics and Well Written Essays - 750 words

The debate on assisted suicide - Research Paper ExampleThe debate on assisted suicide Even as medicine seeks to save these extremely sick people, debate continues to rage on whether these deteriorated and tortured lives in excruciating pain should be ended or non. dapple some people contend assisted suicide outright, others feel that legislations to allow physicians to end the lives of patients suffering from terminal illnesses are in order. However, such patients or their guardians or parents consent must be obtained prior to terminating their lives. This paper explores the two sides of the raging debates on assisted suicide.There are several reasons for which cross sections of the population deem the ending of terminally ill patients lives. First, assisted suicide should be legalized since people should be accorded the right to choose whatever they want to do with their lives provided they do not interfere with or endanger others lives. That is, peoples right to choose freely s hould also cover the right to choose when to end own life. People whose diseases or checkout cannot allow them to end their lives should have the right to be assisted to end their lives and such a right should be granted and respected. Second, assisted suicide should be legalized since, as humilitary personnel beings, we have the duty and responsibility to relieve or end the suffering of other human beings and respect their wishes and dignity. It should be noted that veritable diseases and conditions may make people lose their earlier dignity and they would rather choose to die than live in such dignity. In fact, certain sure conditions are so excruciating that some people are no longer able to function with dignity as they used to do (Terman et al., 2007). It is therefrom not only cruel but also inhumane to deny such be the merciful end to their misery, pain, and indignity by terming their please illegal. Human ruth also dictates that we should comply with such pleas and coope rate with the patients wishes. Opposing aided Suicide On the other side of the debate are those opposed to the idea of assisted suicide. Their first reason for opposing the legalization of assisted suicide is that people have the moral duty to preserve and protect the lives of others. Assisted suicide is hence a fundamental breach of our duty to respect human life. In other words, given that the society should be committed to defend all forms of life, it would be an unfathomable sin to end a fellow human beings life by commissioning its destruction. It is also mans duty to oppose any laws that would support assisted suicide, more so for patients who are innocent people (Humphrey, 2002). Third, those opposed to assisted suicide conjure up that there is no exact definition of the lives that should be ended. This situation would give room for the arbitrary ending of lives deemed worthless or undesirable. In fact, cases of inconvenienced relatives and friends persuading and coercing their ailing relatives to rent for assisted suicide would be a routine thing if assisted suicide were legalized. Worse still, patients may sign assisted suicide requests but wobble their minds later when their conditions may not allow them to make their change of mind known (Hayden, 1999). In such a case, someone may end up being assisted to die against

Sunday, June 9, 2019

Take a stand for or against the proposition Jakob Nielsen should be Essay

Take a stand for or against the proposition Jakob Nielsen should be empowered to set mandatory usability standards for mesh web pages - Essay Example harmonise to Nielsons web site user interface usability is higher for intranets than for the internet. The reason for this lies in the intranets usability design and in the item that an intranet is controlled and a user wont find themselves at a dead link, or fraudulent site (as can happen on the internet). According to Nielsons website (useit.com) the internet is the interface to a vast amount of information, and so the emphasis must be on usability.According to Frank Spiller (Spiller, 2004) Jakob Nielson promotes opera hat practices, he preaches obedience to his guidelines and when he postulates opinions they are interpreted as instructions. Spiller argues that Nielson may be interpreted wrongly and when translated, from the Danish, meanings get lost or misunderstood. The translations do sound a bit egocentric as Nielson declares t hat In the future, first of all, websites will be designed by my guidelines. It is here that the argument moves out-of-door from usability into the realm of personality and professional ethics problems (Spiller, 2004). Nielson comes across as flamboyant and arrogant. He often cites his work a we but doesnt mention the others he is working with. His professional ethics have been questioned on some occasions. For example, he charges 35,000 for a half day consulting appearance while claiming that usability is the least expensive behavior to go (Spiller, 2004).There are many arguments against usability as introduced by Jakob Nielson that include Who will pilot a new usability program? Who will mandate the standards and jibe compliance? What will happen to those who choose not to follow Nielsons standards? Will their websites be denied web access? Will those trying to access denied sites be redirected to another web address? Any mandated plan will need to be well thought out. Perhaps Nielson needs to visit the

Saturday, June 8, 2019

William Shakespeare Quotes and Quotations Essay Example for Free

William Shakespe atomic number 18 Quotes and Quotations EssayFamous Quotes and Quotations from the plays of William Shakespeare Shakespearean quotations such as To be, or not to be and O Romeo, Romeo wherefore art thou Romeo? form some of literatures most celebrated lines and if asked to recite one of William Shakespeares most famous quotes or quotations the absolute majority of people would choose one of these. However, many expressions that we use every day originated in William Shakespeares plays.We use the Bards words all of the time in everyday speech, however, we are often totally unaware that we are borrowing sayings from his work William Shakespeare is attributed with writing 38 plays, Famous Shakespearean sonnets and 5 other poems and used about 21,000 opposite words. William Shakespeare is credited by the Oxford side Dictionary with the introduction of nearly 3,000 words into the language. Its no wonder that expressions from the works of William Shakespeare stool b ecome anonymous parts of the English language.William Shakespeare Quotes Plagiarism The words and quotes of the William Shakespeare can be found everywhere Shakespearean quotations can be heard on the radio and television on a daily basis. The advertising media love to make use of William Shakespeare quotes and sayings. Famous authors have even used Shakespearean quotations as titles for their books such Aldous Huxley and Brave New World. And speech of famous authors did you know that What the dickens was one of the quotes used by William Shakespeare, long before Charles Dickens was born?Other famous Shakespearean quotations such as Ill not budge an inch, We have seen better days ,A dish fit for the gods are all used frequently and, almost as a parody, the expression its Greek to me is often used to describe a frustrated students view of Shakespeares work Politicians dig deep into their pool of William Shakespeare quotes and quotations such as just Play, Foregone Conclusion , One Fell Swoop, and Into Thin Air . Furthermore, other Shakespearean quotes such as to thine own self be true have become widely spoken pearls of wisdom.So quotes from William Shakespeare have now become household words and sayings and just to emphasise the point household word is likewise one of the Bards anonymous quotations Some Famous examples of William Shakespeare Quotes and Quotations To be, or not to be that is the question. Hamlet (Act III, Scene I). Neither a borrower nor a lender be For loan oft loses both itself and friend, and borrowing dulls the edge of husbandry. Hamlet (Act I, Scene III). This above all to thine own self be true. Hamlet (Act I, Scene III).Friends, Romans, countrymen, lend me your ears I come to bury Caesar, not to praise him. (Act III, Scene II). But, for my own part, it was Greek to me. (Act I, Scene II). The course of true love never did run smooth. (Act I, Scene I). scoop Known William Shakespeare Quotes and Quotations The most celebrated of William Shakespeares sayings and quotations from each of his famous plays are listed below. Full details of the plays by William Shakespeare, together with their full scripts, may be accessed via each plays ad hoc section. forwarded from. http//www. william-shakespeare. info/william-shakespeare-quotes. htm

Friday, June 7, 2019

Organizational Behavior And Communication Paper Essay Example for Free

Organizational Behavior And Communication Paper Essay southwesterly Airlines Organizational Behavior Communication Paper true heath Sepulveda Communications for Accountants/Com 530 January 30, 2012 southwestern United States Airlines Organizational Behavior Communication Paper Airlines, such as Southwest Airlines, strive to provide the best customer service that they discount offer to keep their customers happy. A prospective Southwest passenger whitethorn probably make their reservation by calling the customer service number, enter on to the associations website, or booking at an airport with a Southwest Airlines agent.The employees that assist these prospective and actual passengers are attended the backbone of the company and do their best to represent Southwest in the finest way possible. One may question, what makes these employees happy? What kind of organization polish are they surrounded by on a daily basis? A strong organizational cultivation provides stabil ity to an organization (Robbins Judge. , 2011, pg. 520). Culture of Southwest AirlinesAccording to Southwest Airlines bursting chargeary post statement, Employees will be provided the same concern, respect, and caring attitude within the organization that they are expected to share externally with every Southwest Customer (Southwest Airlines, 2012). This in spades collections a positive sign that the majority of employees working for this corporation are happy. As an unemployed individual looking for employment, a position within Southwest is where they would want to be. Its evident that this company values their employees and strives to keep them happy. Happy Employees = Happy Customers. Happy Customers keep Southwest flying (Southwest Airline, 2012). Recently, Southwest Airlines was honored as one of the best companies to work for. Southwest Airlines (NYSE LUV)has been recognized as one of the top 50 Best Places to Work, a significant achievement, as nearly 150,000 companies a re rated by their employees on Glassdoor (PR Newswire, 2011). This point certainly proves that this organizations espoused values align with its enacted values. Communication Roles within Southwest Airlines CompanyAn organizations culture plays a critical role in the way communication is done throughout the company. Southwest airlines, for exercising is a huge company with thousands of employees. One would hypothesise that communication within this organization takes more of a virtual approach. However, just because they are a huge company, doesnt mean that communication with others or the voices of direction wont be casual. As Kelleher, CEO of Southwest, said himself Theres a lot being said about the importance of communication, for instance.But it cant be rigid it cant be formal. It has to proceed directly from the heart. It has to be spontaneous it has to be between individuals seeing each other on the elevator (Lee, 1994). This corresponds to the culture of the organization t hat Kelleher works very hard to maintain. As a CEO who values his employees, we see here that hes not afraid to show how he is and how much he believes in making the environment a happy and comfortable one for his employees. Perceptions Within Southwest AirlinesLets consider an employee of one of Southwest competitors wishing that they worked for this airline instead of their current employer. Hearing all the wonderful stories about working for this company and how happy everyone is leads this employee to think that he/she is working for the wrong company. The perception here is that an employee at Southwest is happier than an employee working for the competitor. Robbins Judge defines Perceptions as, a process by which individuals organize and interpret their sensory impressions in order to give meaning to their environment (Robbins Judge, 2011. g 168). Additionally, they mention that what we perceive may not be what the situation actually turns out to be. Reading information or l istening to others rant about how wonderful the culture is within a company doesnt necessarily mean its all life-threatening. While employees may be happier than miserable working for Southwest, I highly doubt that there arent challenges that are faced at times in their positions. Research has shown that Southwest Airlines espoused values mirrors their enacted values. However, suppose it didnt.What happens if the perceptions of their culture, communication and work environment is said to be peachy, however it really isnt? Suppose employees were really unhappy and the mission statement of Southwest really wasnt followed in the way they operate their organization. This leads to bad perceptions, along with potential employees customers assuming that this organization is voicing something that its not. This is an example of how misalignment between espoused values and enacted values would affect perceptions within Southwest Airlines organization.Conflict within Southwest Airlines Conf lict is another important topic that should be considered in organizations like Southwest Airlines. Conflict results from differences between group members differences in personality, perception, information, culture, and power or influence (Beebe Masterson, 2009. , pg 152). Conflict is something that every company and individual deal with at some point in time. While some people may view conflicts as a bad thing, in actuality and depending on the situations elusive, the conflict may be viewed as a great learning experience.Southwest Airlines view conflicts as a way to strengthen and build relationships (Gittel, 2003, Chapter 8). The individuals that are initially involved in the conflicts should first try to come to an agreement. Its best to make sure that the conflict isnt over a misunderstanding or something thats not an issue. If an agreement or resolution cant be agreed upon, it may be wise to get the other member of the police squad or group involved. When conflicts arise a t Southwest and are not resolved by the parties themselves, a conflict resolution process is used (Gittel, 2003, Chapter 8). acquire others involved will likely help determine why there is a disagreement and somehow find the resolution that the parties couldnt come to on their own. Southwest Airlines is one the most prosperous airlines in the US today. Many of the other Airlines try to use the methods that Southwest employs to keep their company, staff and employees in good standing. The mission of Southwest Airlines is dedication to the highest quality of Customer Service delivered with a sense of warmth, friendliness, individual pride, and Company Spirit.

Thursday, June 6, 2019

Machiavelli’s The Prince Essay Example for Free

Machiavellis The Prince EssayIn Machiavellis The Prince, he plunged into how a prince could bulwark his position once he reaches the top. superstar of the many ways of how to secure a princes position is conquest by criminal virtue. In conquest by criminal virtue, Michiavelli said that a prince secures his position when he reaches the top because it takes a long time and a lot of hard work to prosper. So to make sure no bingle takes away their position, the prince crushes his opponents and earns obeisance from the muckle as much as possible. The prince also makes fewer compromises with their allies, trying to stand alone because he believes he is more enough and stronger than the others. A prince must also know how to reform orders. This may cause havoc because people who benefited the old order might oppose the prince but he must cast off the power to force the people to continue supporting him even though they are already having second thoughts. So why does this rest even though every pol and every citizen who thinks rationally knows that this is im clean. We humans are naturally driven by our hunger for power, fame and fortune.We set aside moral values and ethical values just to quench our self-interests. Politicians act on it because they know this is the easiest way to eliminate a threat. This is a permanent thing so when an enemy ceases to exist, hes permanently gone from the competition and this gives the other politician a peace of mind because he knows that he will take for sure if he has no opponent. Citizens do not act upon this because first, citizens that belong to the lower class are afraid. How could they go against someone so powerful that this person could end their life with just a snap of their fingers?The span and extent of power of this kind of politician is vague that it might extend to having the upper fall out and control over criminals and we never know what he will do just to preserve his power, fame and fortune. Second, around citizens who know about the wrong doings of this politician is paid and given a lot of consolations for their support and silence. As I said, we humans are naturally driven by our hunger by fortune. For people who do not work and believe in gaining money from a real job, this is the most convenient way of earning money because they dont have to do anything but tay silent, run a few errands for the politician and write the politicians name on their ballot every time he runs for a seat.There is also the fact that when local citizens support this politician, they are more secured and well protected. People who try to clash with these local citizens would already odor threaten beforehand because the politician will back them up in part of their deal for the secrecy of the politicians dirty work. This is one of the most immoral acts performed in politics, but one that somehow we can never get rid of.

Wednesday, June 5, 2019

Importance of Natural Product Synthesis

Importance of Natural Product SynthesisHistory of practice of medicine dates back practic each(prenominal)y to the humans of human civilization. Historically, the majority of new drugs have been generated from lifelike products and from compounds derived from natural products. Natural products, including plants, animals and minerals have always been a source of cure agents for many years. Natural products sometimes exhibit pharmacological or biological property that clear be of therapeutic benefit in treating diseases. As such, natural products are the wide awake components not only of mosttraditional medicinesbut also of many newer medications. Furthermore, synthetic analogs of natural products with improved potency and safety can be prepared and therefore natural products are often used as Lead Copmpounds fordrug discovery. In fact, natural products are the inspiration for about one half of U.S. Food and Drug Administration-approved drugs.The birth of the natural product deductive reasoning dates back to 1828 when Friedrich Whler synthesized urea, a naturally occurring substance from ammonium cyanate. This outlet as trivial as it may seem by todays standards not only gave birth to a boundless science called fundamental tax write-off but also contributed to a demystification of mother Nature by burying the fact that synthesis of natures molecules is her exclusive do primary(prenominal). The second major achievement in the field of total synthesis is the synthesis of acetic acid from elemental carbon by Kolbe3 in 1845. It is historically significant because Kolbe coined the give-and-take Synthesis for the first time to describe the process of assembling a chemical compound from other substances. The total synthesis of naturally occurring pigments alizarin in 1869 by Graebe and Liebermann and indigo in 1878 by Baeyer represent landmark accomplishments in the field. Probably, after urea, the most spectacular total synthesis of the nineteenth centu ry was that of Emil Fischers ()-glucose not only for the complexity of the target but also for the considerable stereochemical control that accompanied it. show 1Although the precedent was set in the nineteenth century, it was only in the twentieth century the field of total synthesis started to flourish when Robert Burns Woodward synthesized Quinine. This event ushered in the modern era of total synthesis and Woodward who received the 1965 Nobel Prize for Chemistry for several brilliant examples of total synthesis such as his 1954 synthesis of strychnine, cholesterol5 is regarded as the father of modern organic synthesis.Figure 2Today the art of organic synthesis has improved to astoundingly high levels of sophistication. Through its practice, chemists are able to synthesize organic molecules of all types of structural motifs and for all intents and purposes.Some modern classical examples of total synthesis allow in the synthesis of prostaglandin PG2 and Ginkgolide by E. J Corey, Ingenol by Wood, Brevetoxin by Nicolaou, Vancomycin by Evans, Taxol by Holton6, Nicolaou7, Wender and Danishefsky8 groups independently.The subject of natural product synthesis today, is an important field of investigation whose dividends stretch from new scientific knowledge to practical applications. Considered by many as the flagship of organic synthesis, natural product synthesis symbolizes the power of chemical synthesis at any given time and defines its scope and limitations. It also serves to improve chemical synthesis by attempting to push its frontiers into higher molecular complexity, diversity, and efficiency.they can synthesize not only the molecules of nature and their analogues, but also myriad other organic molecules for authority applications in many areas of science, technology and everyday lifeIntroduction to THF-containing natural productsTetrahydrofuran (THF)-containing natural products widely occur in several important families of biologically active compounds , such as the annonaceous acetogenins 1 and polyether antibiotics isolated from Streptomyces organisms (ionomycin, lonomycins AC, or monensin) 2.Its worthwhile at this juncture to discuss few THF ring containing natural products such as which have been of paramount importance to the mankind and also to the researchers who have been actively involved in the synthesis and isolation of these natural products.AcetogeninsAcetogenins abbreviated as AAGs are a group of THF-Containing natural products isolated from Annonacae species which are vastly distributed in tropical and subtropical regions. They exhibit different biological activities such as antitumor, ant-imalarial, anti microbial, anti protozoal, pesticidal activities2. The common structural features of acetogenins include several free hydroxy groups with various stereo centers, differently located oxygenated functional groups and tetrahydrofuran (THF) ring(s) along the long hydrocarbon twine with an , -unsaturated -lactone moiet y at the end.Uvaricin, a bis THF acetogenin was the first of the AAGs isolated from Uvaria acuminata in 1982. It exhibited blotto anti-cancer activity by inhibiting NADH cubicles in the mitochondrion. The total synthesis of Hexepi-Uvaricin was published by Hoye in 1994 and subsequently first total synthesis was achieved by Keinan in 1998.Montanacin D is a non classical acetogenin isolated from the ethanolic extract of the leaves of Annona Montana16 by Qin group in 1999, possessing a 4,8-cis THP ring along with a 16,19-trans THF ring.IonomycinAmphidinolidesAmphidinolides constitute a series of unique cytotoxic polyketide macrolides obtained from marine symbiotic dinoflagellates of the genus Amphidinium, which are symbionts of Okinawan marine flatworms Amphiscolops spp.1 They exhibit potent cytotoxic activity against murine lymphoma L1210 cells and human epidermoid carcinoma KB cells. Given below are some important Amphidinolides that incorporate a THF-ring in their structurePecten otoxinsPectenotoxin (PTX)-group toxins are a group of polyether macrolide compounds found in microalgae and bivalve molluscs of Australia, Japan, New Zealand and some parts of Europe. Their presence in shellfish was discovered due to their high sharp-worded toxicity in the mouse bioassay after intraperitoneal (i.p.) injections of lipophilic extracts of shellfish. Pectinotoxins are exclusively produced by Dinophysis species. In shellfish they are always accompanied by closely related okadaic acid (OA)-group toxins.The common structural features of (PTX)-group toxins include a spiroketal group, three THF-rings, a bicyclic ketal and a six-membered cyclic hemiketal (Allingham et al., 2007). PTX2 is beleived to be the main precursor, from which many PTX-group toxins are derived through biotransformation during metabolism in the gut of bivalves. It is suggested that an oxidation of PTX2 occurs, leading to the formation of other PTX-group toxins, including PTX1, PTX3, and PTX6PTX-group to xins have been shown to cause cell cycle arrest, cell death and apoptosis. The wide range (10-9 and 10-6 M) of effective concentrations of PTX-group toxins as well as the apparent resistance of some cell lines to the cytotoxic effect of PTX-group toxins indicate the existence of cell-specific factors affecting the sensitivity of biological systems to this group of natural compounds. Studies have confirmed that PTX2 induces apoptosis in several cell lines through multiple mechanisms, involving the perturbation of the cell cycle machinery, inhibition of mitotic separation and cytokinesis through the depolymerization of actin filaments.Oscillariolide and PhormidolideOscillariolide is a halogenated macrolide isolated from a marine blue-green alga Oscillatoria sp. from Gokashowan-Bay, Mie Prefecture. It exhibits significant cytotoxic activity in the echinoderm junkie assay. Phormidolide, a closely related macrolide was isolated from the extract of a laboratory culture of an Indonesian i solate of the cyanobacterium Phormidium sp. It displayed cytotoxicity towards drine shrimp with a LC50 of 1.5 M. The characteristic features of twain oscillariolide and phormidolide include a trisubstituted bridged THF macrolactone with a long polyhydroxy chain containing a unique terminal bromo diene. Structural elucidation revealed that the polyhydroxy side as well as THF ring of both compounds have same stereochemistryChagosensineChagosensine is a sixteen-membered chlorinated macrolide isolated from the methanolic chloroform extract of a bright yellow sponge Leucetta chagosensis usually found in the coral reefs of ablaze(p) Sea, Aqaba Gulf (Israel). the extract of the Leucetta sp. sponge exhibited potent ability to inhibit the epidermal growth factor receptor signaling pathway. A new mechanism for the fulfill of naamidine A and inhibition of tumor cells was shown.